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Iloperidone

SGA • Last reviewed 2025-09-26

Brands: Fanapt

Sources updated 2025 • 1 references

Summary

General Information

Indicated for: Schizophrenia in adults. Second‑generation antipsychotic (SGA)

Dosage & Administration

Typical dose range: 12–24 mg/day (divided)

Indications (label)

Schizophrenia in adults.

View labelExact

Mechanism (brief)

D2/D3 and 5‑HT2A antagonism with high α1 affinity.

Metabolism & Half‑life

  • Metabolism: CYP2D6 and CYP3A4.
  • Half‑life: ~18 h (extensive metabolizers).

Therapeutic Drug Monitoring (TDM)

Recommended: No

References