Skip to content

Oxcarbazepine

Anticonvulsant • Last reviewed 2025-09-26

Brands: Trileptal, Oxtellar XR

Sources updated 20251 references

Summary

General Information

Indicated for: Seizures (partial-onset); sometimes used off-label as adjunctive mood stabilizer. Anticonvulsant

Dosage & Administration

Typical dose range: 900–1500 mg/day (divided or XR)

Indications (label)

Seizures (partial-onset); sometimes used off-label as adjunctive mood stabilizer.

Mechanism (brief)

Voltage-gated sodium channel modulator reducing glutamate release.

Metabolism & Half‑life

  • Metabolism: Cytosolic reduction to active MHD; induces CYP3A4 and UGT.
  • Half‑life: ~9 h (MHD).

Therapeutic Drug Monitoring (TDM)

Recommended: No

References