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Desvenlafaxine

SNRI • Last reviewed 2025-09-26

Brands: Pristiq

Sources updated 2025 • 1 references

Summary

General Information

Indicated for: Major depressive disorder. SNRI

Dosage & Administration

Typical dose range: 50–100 mg once daily

Indications (label)

Major depressive disorder.

View labelExact

Mechanism (brief)

Serotonin and norepinephrine reuptake inhibitor; active metabolite of venlafaxine.

Metabolism & Half‑life

  • Metabolism: Phase II (UGT) with minimal CYP2D6 involvement; minor CYP3A4.
  • Half‑life: ~11 h.

Therapeutic Drug Monitoring (TDM)

Recommended: No

References