chlordiazepoxide
Adjunctive therapy • Brands: LIBRIUM
Last reviewed: 2025-12-29
General information
- Class: Adjunctive therapy
- Common US brands: LIBRIUM
- Therapeutic drug monitoring not routinely recommended.
- Last reviewed: 2025-12-29
Dosing & forms
- Forms/strengths: —
- Frequency: —
- Food: —
- Typical range: —
Mechanism (brief)
Benzodiazepine; positive allosteric modulator of GABA-A receptors.
Metabolism & Half‑life
- Metabolism: Hepatic metabolism
- Half‑life: Single-dose range 24–48 h
Therapeutic Drug Monitoring (TDM)
Recommended: No
Monitoring highlights
- —
Sources
- Chlordiazepoxide hydrochloride prescribing information — DailyMed (2025)
- ASAM guideline on benzodiazepines — Journal of Addiction Medicine (2020)
- Evidence-based pharmacological treatment of anxiety disorders — Depression and Anxiety (2014)
- The ASAM Clinical Practice Guideline on Alcohol Withdrawal Management — Journal of Addiction Medicine (2020)