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Citalopram

SSRI • Brands: Celexa

Last reviewed: 2025-09-26

General information

Indicated for: Major depressive disorder.

Dosing & forms

  • Forms/strengths: —
  • Frequency: —
  • Food: —
  • Typical range: 20–40 mg/day

Mechanism (brief)

Selective serotonin reuptake inhibitor (SSRI).

Metabolism & Half‑life

  • Metabolism: CYP2C19, CYP3A4, and CYP2D6 pathways.
  • Half‑life: ~35 h (longer in elderly/hepatic impairment).

Therapeutic Drug Monitoring (TDM)

Recommended: No

View labelExact

Monitoring highlights

  • ECG/QTc when doses >20 mg or cardiac risk factors — Baseline and as indicated
  • Serum sodium in older adults or diuretic use — Baseline and periodically

Sources