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Fluphenazine

FGA • Last reviewed 2025-09-26

Brands: Prolixin

Sources updated 2025 • 1 references

Summary

General Information

Indicated for: Schizophrenia; psychotic disorders (oral and depot). First‑generation antipsychotic (FGA)

Dosage & Administration

Typical dose range: 5–20 mg/day (divided)

Indications (label)

Schizophrenia; psychotic disorders (oral and depot).

View labelExact

Mechanism (brief)

High-potency phenothiazine D2 antagonist.

Metabolism & Half‑life

  • Metabolism: CYP2D6.
  • Half‑life: ~15 h (oral); decanoate apparent half-life 7–10 days.

Therapeutic Drug Monitoring (TDM)

Recommended: No

References