Fluvoxamine

General information

Indicated for: Obsessive-compulsive disorder; social anxiety disorder.

Dosing & forms

• Forms/strengths: —
• Frequency: —
• Food: —
• Typical range: 100–300 mg/day (divided or XR once daily)

Mechanism (brief)

Selective serotonin reuptake inhibitor (SSRI).

Metabolism & Half‑life

• Metabolism: CYP1A2, CYP2C19, CYP2D6 (also strong inhibitor of CYP1A2/2C19).
• Half‑life: ~15–22 h (longer at steady state).

Therapeutic Drug Monitoring (TDM)

Recommended: No

Monitoring highlights

• Assess for sedation and GI effects — During initiation
• Review drug interactions (CYP1A2/2C19 inhibition) — Each visit with med changes

Sources

• Fluvoxamine label — DailyMed (2025)