fluvoxamine
Adjunctive therapy • Brands: Luvox
Last reviewed: 2025-10-05
General information
- Class: Adjunctive therapy
- Common US brands: Luvox
- Therapeutic drug monitoring not routinely recommended.
- Last reviewed: 2025-10-05
Dosing & forms
- Forms/strengths: —
- Frequency: —
- Food: —
- Typical range: —
Mechanism (brief)
Selective serotonin reuptake inhibitor (SSRI).
Metabolism & Half‑life
- Metabolism: CYP1A2, CYP2D6, CYP2C19
- Half‑life: Single-dose mean 15 h; Steady-state mean 22 h
Therapeutic Drug Monitoring (TDM)
Recommended: No
Monitoring highlights
- —
Sources
- Fluvoxamine maleate tablets prescribing information — DailyMed (2025)
- APA Clinical Practice Guideline for the Treatment of Patients With Obsessive-Compulsive Disorder — American Psychiatric Association (2020)
- CANMAT 2024 Clinical Guidelines for the Management of Major Depressive Disorder — Canadian Journal of Psychiatry (2024)
- Consensus Guidelines for Therapeutic Drug Monitoring in Neuropsychopharmacology: Update 2017 — Pharmacopsychiatry (2018)
- Efficacy of fluvoxamine in obsessive-compulsive disorder: a double-blind comparison with placebo — Archives of General Psychiatry (1989)