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Oxcarbazepine

Anticonvulsant • Brands: Trileptal, Oxtellar XR

Last reviewed: 2025-09-26

General information

Indicated for: Seizures (partial-onset); sometimes used off-label as adjunctive mood stabilizer.

Dosing & forms

  • Forms/strengths: —
  • Frequency: —
  • Food: —
  • Typical range: 900–1500 mg/day (divided or XR)

Mechanism (brief)

Voltage-gated sodium channel modulator reducing glutamate release.

Metabolism & Half‑life

  • Metabolism: Cytosolic reduction to active MHD, induces CYP3A4 and UGT.
  • Half‑life: ~9 h (MHD).

Therapeutic Drug Monitoring (TDM)

Recommended: No

View labelExact

Monitoring highlights

  • Serum sodium — Baseline, after titration, periodically
  • CBC/LFTs — Baseline and as indicated

Sources