prazosin
Adjunctive therapy • Brands: MINIPRESS
Last reviewed: 2025-12-28
General information
- Class: Adjunctive therapy
- Common US brands: MINIPRESS
- Therapeutic drug monitoring not routinely recommended.
- Last reviewed: 2025-12-28
Dosing & forms
- Forms/strengths: —
- Frequency: —
- Food: —
- Typical range: —
Mechanism (brief)
Alpha-1 adrenergic antagonist; reduces sympathetic tone (vasodilation).
Metabolism & Half‑life
- Metabolism: Hepatic
- Half‑life: Single-dose range 2–3 h
Therapeutic Drug Monitoring (TDM)
Recommended: No
Monitoring highlights
- —
Sources
- Prazosin hydrochloride prescribing information — DailyMed (2025)
- Trial of prazosin for post-traumatic stress disorder in military veterans — The New England Journal of Medicine (2018)
- Prazosin for treatment of post-traumatic stress disorder — CNS Spectrums (2021)
- Treatment Guidelines for PTSD — Journal of Clinical Medicine (2021)