propranolol
Adjunctive therapy • Brands: INDERAL, INDERAL LA
Last reviewed: 2025-12-29
General information
- Class: Adjunctive therapy
- Common US brands: INDERAL, INDERAL LA
- Therapeutic drug monitoring not routinely recommended.
- Last reviewed: 2025-12-29
Dosing & forms
- Forms/strengths: —
- Frequency: —
- Food: —
- Typical range: —
Mechanism (brief)
Nonselective beta-adrenergic receptor blocker (beta-1/beta-2 antagonism).
Metabolism & Half‑life
- Metabolism: CYP2D6, CYP1A2, CYP2C19, Glucuronidation
- Half‑life: Single-dose range 3–6 h
Therapeutic Drug Monitoring (TDM)
Recommended: No
Monitoring highlights
- —
Sources
- Propranolol hydrochloride tablets prescribing information — DailyMed (2025)
- Propranolol for the treatment of anxiety disorders — Journal of Psychopharmacology (2016)
- Beta-blockers for the treatment of anxiety disorders — Journal of Affective Disorders (2025)
- Neuroleptic-induced akathisia — propranolol versus benztropine — Biological Psychiatry (1988)