Sertraline

General information

Indicated for: Sertraline hydrochloride tablets are a selective serotonin reuptake inhibitor (SSRI) indicated for the treatment of ( 1 ): Major depressive disorder (MDD) Obsessive-compulsive disorder (OCD) Panic disorder (PD) Posttraumatic stress disorder (PTSD) Social anxiety disorder (SAD) Premenstrual dysphoric disorder (PMDD)

Dosing & forms

• Forms/strengths: —
• Frequency: —
• Food: —
• Typical range: 50–200 mg/day

Mechanism (brief)

Selective serotonin reuptake inhibitor (SSRI).

Metabolism & Half‑life

• Metabolism: Multiple CYPs, fewer DDIs relative to fluoxetine/paroxetine.
• Half‑life: ~26 h.

Therapeutic Drug Monitoring (TDM)

Recommended: No

Monitoring highlights

• —

Sources

• Sertraline label — DailyMed (2025)